Effect of ceruloplasmin on AoPR8 influenza virus infection in embryonate eggs and mice

Tomas, E.; Samuel, I.

Virologie 26(1): 57-61

1975


ISSN/ISBN: 0253-181X
PMID: 1216690
Document Number: 95621
Inoculation to embryonate hen eggs and mice of AoPR8 influenza virus pre-incubated with ceruloplasmin (10(-7)-10(-6) M) results in a statistically significant decrease in the hemagglutinating titer of the virus, without changes in infectivity. This effect is ascribed to formation of a virus-ceruloplasmin complex, which probably interferes with both virus penetration and release of newly formed virus from the cell.

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