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A comparative study of activity of nucleic acid metabolism in human embryonic liver

Borzenko, B.H.; Drel', K.O.

Ukrains'kyi Biokhimichnyi Zhurnal 47(6): 724-727

1975

ISSN/ISBN: 0041-610X
PMID: 1202705
Document Number: 94753
In nuclei of hepatocytes of human embryos from the 18th to 40th week of antenatal development the activity of synthesis enzymes lowers: thymidine kinase is 7 times at low, uridine kinase - 11 times as low. In parallel during the same period a decrease in the activity of nucleases drops: DNase - by 15 times, RNase - by 11 times. The activity of these enzymes in the liver of adult persons (22-35 years old) is similar to their activity in the liver of human embryo to the moment of birth.

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