Proline biosynthesis and degradation in mammalian cells and tissue
Phang, J.M.; Valle, D.; Kowaloff, E.M.
Annals of Clinical and Laboratory Science 5(4): 298-302
1975
ISSN/ISBN: 0091-7370 PMID: 1163994 Document Number: 90747
Radioisotopic assays have been developed for the enzymes of proline metabolism. These assays are specific and sensitive enough to measure enzyme activities in cultured cells and biopsy specimens. Measurements of these enzymes in tissues and cultured cells suggest that endogenous biosynthesis of proline may be an important source of this amino acid.
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