Glycemic indices in animals at different stages of hypokinesia and with administration of glucose, adrenaline and insulin
Chernyĭ, A.V.
Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 9(1): 23-27
1975
ISSN/ISBN: 0321-5040 PMID: 1113488 Document Number: 87981
The sugar content in the blood was measured (and sugar curves were plotted) in healthy rats and in rats during the 15, 30, 60 and 90th hypokinetic days after they were injected with glucose at a dose of 4 g/kg, epinephrine at a dose of 150 mg/kg and insulin at a dose of 0.5 u/kg. The three glycemic parameters were determined: 1) the coefficient of maximum hyper- and hypoglycemia; 2) the intensity of hyper- and hypoglycemia and 3) the hyper- and hypoglycemic limit. An analysis of the sugar plots and the above coefficients showed an increased sensitivity to insulin, an elevated tolerance to glucose and a less distinct response to epinephrine.