Effect of mechanical means on the restoration of the limb regenerative ability in metamorphic stages of Bufo regularis Reuss
Michael, M.I.; Aziz, F.K.
Acta Biologica Academiae Scientiarum Hungaricae 26(1-2): 15-21
1975
ISSN/ISBN: 0001-5288 PMID: 1220487 Document Number: 87311
Limbs of B. regularis Reuss metamorphic stages 57, 63 and 66 were transected at the thigh level. Removal of the apical skin cover on the 3rd postoperative day, followed by traumatization after further 2 days in the limb stumps, was more effective in the enhancement of the regenerative ability than when each was performed independently. Better results were achieved in cases of the preclimatic stage (57) where about 30% of the cases developed heteromorphic limb outgrowths having more distal structures as the shank ending with or without toes. Normally, after transection at the same level, the limb stumps of this stage could restore part of the thigh region only.