Bufadienolides from venom of Bufo bufo gargarizans
Zhang, P.-W.; Jiang, R.-W.; Ye, W.-C.; Tian, H.-Y.
Zhongguo Zhong Yao Za Zhi 39(5): 841-845
2014
ISSN/ISBN: 1001-5302 PMID: 25204176 Document Number: 677224
Twelve compounds were isolated from the venom of Bufo bufo gargarizans. On the basis of their physical and chemical properties and spectral data, their structures were identified as resibufagenin (1), bufotalin (2), desacetylcinobufagin (3), 19-oxodesacetylcinobufotalin (4), cinobufotalin (5), 1beta-hydroxylbufalin (6), 12alpha-hydroxybufalin (7), bufotalinin (8), Hellebrigenin (9), telocinobufagin (10), hellebrigenol (11) and cinobufagin-3-hemisuberate methyl ester (12), respectively. Compounds 7 and 12 are new natural products.