Isolation, purification and chemical composition of insoluble collagen from Guerin epithelioma
Bańkowski, E.; Galasiński, W.; Gindzieẃski, A.; Rzeczycki, W.
Acta Biochimica Polonica 22(3): 221-227
1975
ISSN/ISBN: 0001-527X PMID: 1179910 Document Number: 84787
1. The insoluble collagen from Guerin epithelioma was isolated and its chemical composition was determined. The unusually high histidine content is accompanied in tumour collagen by a relatively small amount of lysine and arginine. 2. The isolated protein was strongly bound to glycoprotein, which could not be removed by EDTA treatment unless this procedure was preceded by digestion of the complex with trypsin.