Experimental infection of lambs with an adenovirus isolated from sheep and related to bovine adenovirus type 2. I. Virological studies
Belák, S.; Pálfi, V.; Tury, E.
Acta Veterinaria Academiae Scientiarum Hungaricae 25(1): 91-95
1975
ISSN/ISBN: 0001-7205 PMID: 171937 Document Number: 83624
Colostrum-deprived lambs were experimentally infected with adenovirus strain Het/3. The strain, isolated from sheep with respiratory symptoms, is related to type 2 bovine adenovirus. The virus was found to be pathogenic for lambs. Respiratory and intestinal symptoms were observed with a mild rise of temperature. Susceptible lambs showed similar symptoms after contact infection. Three out of nine infected animals died on post-infection days 1, 2 and 9, the others were killed between days 4 and 13. The lambs shed the virus both in their nasal discharges and faeces. Virus-neutralizing antibodies up to a serum dilution of 1:8 - 1:128 appeared in the sera of the infected animals. On the basis of detailed observations evidence is presented that the Het/3 virus can cause a respiratory and intestinal disease in lambs.