Infectivity of bovine C- type (leukemia) virus for sheep and goats
Hoss, H.E.; Olson, C.
American Journal of Veterinary Research 35(5): 633-637
1974
ISSN/ISBN: 0002-9645 PMID: 4364455 Document Number: 78026
Of 41 lambs given infective bovine C-type virus i/p, 33 developed evidence (demonstrable C-type virus, persisting or late-developing precipitins) of infection within 14 months. Evidence of infection appeared earlier in the lambs when the dose of lymphocyte culture was increased. Infection was produced in lambs given cultures kept at -60 deg C for 10 to 14 days. Six- to eight-week-old lambs given lymphocyte culture i/p became infected. Lambs given culture orally did not have evidence of infection up to 14 months later. Buffy coat suspensions from two sheep with experimentally produced lymphosarcoma were infective for seven lambs, one of which died with lymphosarcoma at 13 months of age. Infection was established in 3 of 4 calves and in 5 of 5 goats inoculated with bovine C-type virus from infected sheep.