Experimental transmission of the stomatitis pneumoenteritis complex to sheep and goats
Mann, E.; Isoun, T.T.; Fabiyi, A.; Odegbo-Olukoya, O.O.
Bulletin of Epizootic Diseases of Africa 22(2): 99-103
1974
ISSN/ISBN: 0007-487X PMID: 4471440 Document Number: 77579
Tissue culture (sheep embryo kidney) and crude material from a sheep which died from 'peste des petits ruminants' (PPR) and goats which died from 'kata' was given intranasally or orally to 8 sheep and 8 goats. Some developed a mild form of the disease, with a febrile reaction after 7-11 days and occasionally diarrhoea, but none developed oral lesions. The acute form of the disease was not reproduced, possibly because it required repeated challenge, or because the inocula which had been produced from sheep had been stored at -70 deg C for a year before use. Two young Sokoto red goats showing nasal and ocular discharges were kept with four recovered experimental animals and three controls (both sheep and goats). The Sokoto goats and controls died from 'kata', but the experimental animals developed less severe symptoms, and all but one sheep recovered. Symptoms of 'kata' in sheep and goats included nasal and ocular discharge, diarrhoea, oral and enteric erosions, rhinitis and catarrhal enteritis. Exudative pneumonia occurred only in goats. A filtrable agent which produced CPE within 24-48 hours was isolated from lymph nodes, lungs and intestines of both sheep and goats. Studies are in progress to assess whether the same agent is involved in natural and experimental infection of both sheep and goats.