The effects of Ipomoea carnea on goats and sheep
Damir, H.A.; Adam, S.E.; Tartour, G.
Veterinary and Human Toxicology 29(4): 316-319
1987
ISSN/ISBN: 0145-6296 PMID: 3629912 Document Number: 301919
The signs of Ipomoea poisoning in Nubian goats and Desert sheep orally dosed with fresh and dry leaves and stems of Ipomoea carnea at 2.5, 5 and 10 g/kg day were inappetence, depression, weakness of the hind limbs, dyspnoea, staggering, and pallor of the visible mucous membranes. The main lesions were focal necrosis and fatty vacuolation of centrilobular hepatocytes, accumulation of fibroblasts in hepatic portal tracts, degeneration or necrosis of the cells of the renal proximal convoluted tubules, haemorrhage in renal cortices, in renal medullas and in cardiac muscle fibres, focal pulmonary oedema and emphysema, and straw-coloured fluid in serous cavities. Increased serum aspartate aminotransferase and ammonia concentrations, and decreased concentrations of total protein, calcium and magnesium in the serum of Ipomoea-poisoned animals were detected. Haematological changes indicated the development of normocytic normochromic anaemia.