A Case of Advanced Esophageal Cancer Successfully Treated with DCF Chemotherapy Followed by Conversion Surgery
Okada, K.; Takeoka, T.; Miki, H.; Kobayashi, K.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 44(12): 1623-1625
2017
ISSN/ISBN: 0385-0684 PMID: 29394722 Document Number: 691656
A 66-year-old man was admitted to our hospital complaining of dysphagia. Endoscopic examination showed type 1 tumor in the middle intrathoracic esophagus. The biopsy specimen showed moderately differentiated squamous cell carcinoma. Abdominal CT scan revealed the swelling of lymph nodes along the celiac artery. We diagnosed unresectable advanced esophageal cancer(cT3N4M0, cStage IV a). Systemic chemotherapy was initiated using a regimen of docetaxel, CDDP, and 5- FU(DCF). Abdominal CT scan indicated regression of the swelling lymph nodes after 3 courses. Subtotal esophagectomy with 3 field lymph nodes dissection was performed, because the bulky lymph node could not be resected. Histological effect of chemotherapy diagnosed from resected specimen was Grade 2. In summary, we experienced a case of esophageal cancer successfully treated with DCF chemotherapy followed by conversion surgery.