Role of polymorphism NO-synthase gene in the pathogenesis of multifactorial diseases
Stepanova, E.I.; Skvarskaia, E.A.
Likars'ka Sprava 2014(5-6): 47-55
2014
ISSN/ISBN: 1019-5297 PMID: 25906647 Document Number: 676449
The review of the literature about the results of the study of the role of 4a/b VNTR-polymorphism of eNOS in pathophysiology of various states of the body. It is shown that the data are ambiguous and sometimes contradictory. The study of the contribution of candidate genes to the implementation of multifactorial diseases can increase the accuracy of prediction of the set of risk factors, early diagnosis facilitate and sufficient therapy of multifactorial diseases.
Document emailed within 1 workday
Related Documents
Gołab-Janowska, M.; Honczarenko, K.; Gawrońska-Szklarz, B.; Potemkowski, A. 2007: The role of NAT2 gene polymorphism in aetiology of the most frequent neurodegenerative diseases with dementia Neurologia i Neurochirurgia Polska 41(5): 388-394Dosenko, V.E.; Zagoriy, V.Y.; Haytovich, N.V.; Gordok, O.A.; Moibenko, A.A. 2006: Allelic polymorphism of endothelial NO-synthase gene and its functional manifestations Acta Biochimica Polonica 53(2): 299-302
Yasujima, M.; Tsutaya, S.; Shoji, M. 1998: Endothelial nitric oxide synthase gene polymorphism and hypertension Rinsho Byori. Japanese Journal of Clinical Pathology 46(12): 1199-1204
Ishida, Y.; Kawakami, K.; Tanaka, Y.; Kanehira, E.; Omura, K.; Watanabe, G. 2002: Association of thymidylate synthase gene polymorphism with its mRNA and protein expression and with prognosis in gastric cancer Anticancer Research 22(5): 2805-2809
Lauten, M.; Asgedom, G.; Welte, K.; Schrappe, M.; Stanulla, M. 2003: Thymidylate synthase gene polymorphism and its association with relapse in childhood B-cell precursor acute lymphoblastic leukemia Haematologica 88(3): 353-354
Boris, K.V.; Kochieva, E.Z.; Kudryavtsev, A.M. 2014: Interspecific polymorphism of the glucosyltransferase domain of the sucrose synthase gene in the genus Malus and related species of Rosaceae Genetika 50(12): 1472-1475
Löffers, C.; Heilig, B.; Hecker, M. 2015: T-786C single nucleotide polymorphism of the endothelial nitric oxide synthase gene as a risk factor for endothelial dysfunction in polymyalgia rheumatica Clinical and Experimental Rheumatology 33(5): 726-730
Kłodowska-Duda, G.A.; Samelska, J.A.; Opala, G.M. 2005: Polymorphism of N-acetyltransferase-2 and pathogenesis of neoplastic diseases Wiadomosci Lekarskie 58(3-4): 212-217
Letonja, M.; Peterlin, B.; Bregar, D.; Petrovic, D. 2005: Are the T/C polymorphism of the CYP17 gene and the tetranucleotide repeat (TTTA) polymorphism of the CYP19 gene genetic markers for premature coronary artery disease in Caucasians? Folia Biologica 51(3): 76-81
Songpatanasilp, T.; Chanprasertyothin, S. 2011: Effects of differences in polymorphism of gene encoding enzyme faenesyl diphosphate synthase (FDPS), rs2297480, on bone mineral density and biochemical markers of bone turnover in Thai postmenopausal women Journal of the Medical Association of Thailand 94(Suppl 5): S38-S46
Sehouli, J.; Mustea, A.; Könsgen, D.; Katsares, I.; Lichtenegger, W. 2002: Polymorphism of IL-1 receptor antagonist gene: role in cancer Anticancer Research 22(6a): 3421-3424
Kuroyama, H.; Sanke, T.; Nanjo, K. 1994: Glycogen synthase gene-glycogen synthase gene in Japanese patients with NIDDM Nihon Rinsho. Japanese Journal of Clinical Medicine 52(10): 2726-2730
Scapoli, L.; Girardi, A.; Palmieri, A.; Martinelli, M.; Cura, F.; Lauritano, D.; Pezzetti, F.; Carinci, F. 2015: Interleukin-6 Gene Polymorphism Modulates the Risk of Periodontal Diseases Journal of Biological Regulators and Homeostatic Agents 29(3 Suppl 1: 111-116
Prystupa, L.N.; Garbuzova, V.Y.; Kmyta, V.V. 2015: Bcl1 Polymorphism of Glucocorticoid Receptor Gene and Respiratory Diseases Likars'ka Sprava 2015(1-2): 43-48
Dehaghani, A.S.; Kashef, M.A.; Ghaemenia, M.; Sarraf, Z.; Khaghanzadeh, N.; Fattahi, M.J.; Ghaderi, A. 2009: PDCD1, CTLA-4 and p53 gene polymorphism and susceptibility to gestational trophoblastic diseases Journal of Reproductive Medicine 54(1): 25-31
Pawlak, A.L.; Strauss, E. 2001: Polymorphism of the methylenetetrahydrofolate reductase gene (MTHFR) and incidence of hyperhomocysteinemia-related diseases Postepy Higieny i Medycyny Doswiadczalnej 55(2): 233-256
Roĭtberg, G.E.; Tikhonravov, A.V.; Dorosh, Z.V. 2003: Role of angiotensin-converting enzyme gene polymorphism in the development of metabolic syndrome Terapevticheskii Arkhiv 75(12): 72-77
Amarapal, P.; Tantivanich, S.; Balachandra, K.; Matsuo, K.; Pitisutithum, P.; Chongsa-nguan, M. 2005: The role of the Tat gene in the pathogenesis of HIV infection Southeast Asian Journal of Tropical Medicine and Public Health 36(2): 352-361
Kaĭdashev, I.P.; Rasin, A.M.; Shlykova, O.A.; Gorbas', I.M.; Smirnova, I.P.; Petrushov, A.V.; Rasin, M.S. 2007: Frequency of the Pro 12Ala polymorphism of PPARgamma2 gene in Ukrainian population and its possible role in development of metabolic syndrome TSitologiia i genetika 41(5): 43-47
Rodríguez-Rodríguez, L.; Castañeda, S.; Vázquez-Rodríguez, T.ás.R.; Morado, I.C.; Gómez-Vaquero, C.; Marí-Alfonso, B.; Miranda-Filloy, J.é A.; Narvaez, J.; Ortego-Centeno, N.; Vicente, E.F.; Blanco, R.; Amigo-Diaz, E.ón.; Fernández-Gutiérrez, B.ín.; Martin, J.; González-Gay, M.A. 2011: Role of the rs6822844 gene polymorphism at the IL2-IL21 region in biopsy-proven giant cell arteritis Clinical and Experimental Rheumatology 29(1 Suppl 64: S12-S16