A case of complete response (CR) persisting for 3 years and 3 months from combination therapy of S-1 and CDDP in a patient with advanced gastric cancer with multiple liver metastases
Sekino, Y.; Okada, M.; Hamada, J.; Tagami, S.; Sakon, M.; Okita, K.; Takata, M.; Seki, H.; Hayashi, K.; Munakata, Y.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 36(5): 847-849
2009
ISSN/ISBN: 0385-0684 PMID: 19461192 Document Number: 631417
The case was a 70-year-old man with type-2 gastric cancer in the lesser curvature accompanied by multiple liver metastases. He received combination chemotherapy of S-1 and CDDP. S-1 was administered at 100 mg/body/day for 21 days followed by withdrawal for 14 days, and CDDP was prescribed at 80 mg/body/day div on day 8. After 3 courses of treatment, the multiple liver metastases disappeared. The primary gastric lesion had changed to a scar and endoscopic biopsy revealed no cancer cell. After the 4th course, we changed the therapy to S-1 alone and after that to UFT alone. Now, 3 years and 3 months after inducing CR, the patient continues to receive UFT with no regrowth of the tumor.