A case of advanced maxillary carcinoma with cervical lymph node metastases showing a complete response to the combination therapy of CDDP, TS-1 and radiation
Hino, S.; Shintani, S.; Nonaka, T.; Hara, S.; Hamakawa, H.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 31(2): 215-217
2004
ISSN/ISBN: 0385-0684 PMID: 14997754 Document Number: 583393
We report a case of right maxillary carcinoma with metastases to the cervical lymph nodes (T4N2cM0, Stage IV). A 76-year-old woman was administered preoperative chemoradiotherapy, followed by curative surgery. TS-1 (80 mg/day), CDDP (5 mg/m2/day) and concurrent radiation (total 40 Gy) induced a complete response. Grade 2 neutropenia, thrombocytopenia and stomatitis were observed. In the primary tumor and cervical metastatic lymph nodes, no viable carcinoma cells were detected and cancer nests were replaced with marked fibrous tissue.
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