A case of gastric cancer with liver metastases achieving a clinical complete response after S-1 plus CDDP therapy
Kumazu, Y.; Aoyama, T.; Yamada, T.; Wada, H.; Kitani, Y.; Yamamoto, N.; Yukawa, N.; Yoshikawa, T.; Rino, Y.; Ozawa, Y.; Masuda, M.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 41(12): 2337-2339
2014
ISSN/ISBN: 0385-0684 PMID: 25731515 Document Number: 676804
We report a case of gastric carcinoma with metastasis to the liver responding to surgery and chemotherapy.The patient was a 74-year-old man with gastric cancer, clinically diagnosed as P0H0M0T3N0.We initially planned to perform an open distal gastrectomy.However, intraoperative findings revealed metastatic tumors in the liver.Therefore, the patient underwent a D1 distal gastrectomy.After surgery, the patient received the following chemotherapy regimens: 1 course of S-1 and 8 courses of a S-1 and cisplatin (CDDP) combination.After 8 courses of S-1 plus CDDP treatment, liver metastases could not be detected by computed tomography (CT), magnetic resonance imaging (MRI), or positron emission tomography (PET). The patient was assessed to have a clinical complete response.Fifty months after surgery, the patient is alive without recurrence.