Combined treatment for rectal cancer using different radiomodification means

Barsukov, I.A.; Tkachev, S.I.; Oltarzhevskaia, N.D.; Korovina, M.A.; Iarmolenko, S.P.; Vaĭnson, A.A.; Perevoshchikov, A.G.; Nikolaev, A.V.; Gradiushko, A.T.; Kutateladze, T.O.; Vlasov, O.A.; Malikho, A.G.; Tamrazov, R.I.; Kuz'michev, D.V.; Aliev, V.A.; Mamedli, Z.Z.; Barsukov, I.A; Tkachev, S.I; Oltarzhevskaia, N.D; Korovina, M.A; Iarmolenko, S.P; Vainson, A.A; Perevoshchikov, A.G; Nikolaev, A.V; Gradiushko, A.T; Kutateladze, T.O; Vlasov, O.A; Malikho, A.G; Tamrazov, R.I; Kuz&apo; michev, D.V; Aliev, V.A; Mamedli, Z.Z

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Combined treatment for rectal cancer using different radiomodification means

Barsukov, I.A.; Tkachev, S.I.; Oltarzhevskaia, N.D.; Korovina, M.A.; Iarmolenko, S.P.; Vaĭnson, A.A.; Perevoshchikov, A.G.; Nikolaev, A.V.; Gradiushko, A.T.; Kutateladze, T.O.; Vlasov, O.A.; Malikho, A.G.; Tamrazov, R.I.; Kuz'michev, D.V.; Aliev, V.A.; Mamedli, Z.Z.

Voprosy Onkologii 54(3): 350-353

2008

ISSN/ISBN: 0507-3758

PMID: 18652242

Document Number: 616988

The paper presents an evaluation of the results of surgical and combined treatment received by 961 patients at the Center's Clinics within 28 years. The analysis was based on 3 protocols of prospective randomized study. It dealt with assessment of the end results of surgical and combined treatment for operable rectal cancer using one preoperative hyperfractonated STD of 5-25 Gy. That was combined with local microwave hyperthermia and two radio modifiers--local microwave hyperthermia+intrarectal administration of a preparation containing metronidazolum. Due to the latter factor, the rate of 3-year relapse-free survival rose considerably. Also, loco-regional and distant metastasis incidence was cut down due to superior ablasticity of surgery.