Report of a Successful Case of Combined Modality Therapy for a Patient with Local Recurrence of Rectal Cancer
Fukino, N.; Kida, K.; Kuboi, Y.; Mimatsu, K.; Amano, S.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 43(12): 2157-2159
2016
ISSN/ISBN: 0385-0684 PMID: 28133254 Document Number: 686925
A 67-year-old man underwent abdominoperinealresection for rectalcancer (Rb, tub2>muc, A, N1, H0, P0, M0, Cy1, Stage III a). We administered mFOLFOX6 as adjuvant chemotherapy for 6 months. Twenty-seven months after surgery, his serum tumor marker level was increased, and local recurrence in the left rear of the prostate was detected by pelvic CT. The patient selected radiation(50 Gy/25 Fr), after rejecting resection for the local recurrence. After radiation, we performed chemotherapy combined with bevacizumab. Seventeen months from the start of chemotherapy, 47 months after surgery, chemotherapy was stopped because his tumor maker levels normalized and pelvic CT revealed a partial response. At present, his progression-free survival is 7 months after completion of chemotherapy. We conclude that combined modality therapy is an option for a patient with locally recurrent rectal cancer.