Polyradiomodification as component of combined treatment of rectal cancer: rationale and results
Barsukov, I.A.; Tkachev, S.I.; Oltarzhevskaia, N.D.; Perevoshchikov, A.G.; Korovina, M.A.; Nikolaev, A.V.; Glebovskaia, V.V.; Kuz'michev, D.V.; Aliev, V.A.; Mamedli, Z.Z.; Pavlova, A.M.
Voprosy Onkologii 56(1): 66-69
2010
ISSN/ISBN: 0507-3758 PMID: 20361619 Document Number: 641689
The report discusses our 30-year experience with surgical and combined treatment of rectal cancer. In cases of preoperative radiotherapy, loco-regional frequency of relapse dropped to 9.6% as compared with surgery (16.3%). After preoperative thermoradiotherapy it fell to 4.6%; polyradiomodification - 0.5% (3-year follow-up). Distant metastasis formation rates were: after polyradiomodification--1.5%, radiotherapy--9.6%, and thermo-radiotherapy--6%. Recurrence-free survival rates (3 years) were: polyradiomodification--97.3%, thermo-radiotherapy--75.9%, radiotherapy--71.1%, and surgery--58%. Data on regimens and dosage of polyradiomodification alongside radiation damage for different combinations of treatment are presented.