Total ATPases activity in different tissues of albino mice exposed to aluminium acetate
Sushma, N.John.; Rao, K.Jayantha.
Journal of Environmental Biology 28(2 Suppl): 483-484
2007
ISSN/ISBN: 0254-8704 PMID: 17929769 Document Number: 607423
This study has revealed significant variation in total ATPase activity after administration of aluminium acetate in different tissues of albino mice. With sublethal dose (3.5 mg/kg body weight) of aluminium acetate, total ATPase activity was decreased in brain (-50.61), liver (-50.69), kidney (-30.74), heart (-64.07), muscle (-51.50) and testis (-65.53) of albino mice. The decrement was enhanced with the increase of aluminium, acetate. ATPases play an important role in the maintenance of cell permeability and energy transformation in the biological system. The results suggest that ATPase has a particular sensitivity to aluminium acetate.