A rare case of large-cell gastric lymphoma in a patient with chronic lympholeucosis
Simonenko, V.B.; Frank, G.A.; Zavalishina, L.E.; Makanin, M.A.; Ostrovskaia, E.I.; Beliaev, L.B.; Dulin, P.A.
Klinicheskaia Meditsina 84(12): 62-64
2006
ISSN/ISBN: 0023-2149 PMID: 17294889 Document Number: 597092
Chronic lympholeucosis (CLL) is a B-cell lymphoproliferative disease, the morphological substrate of which is a clone of lymphocytes similar in size and morphology to normal mature lymphocyte and similar in immunophenotype to B lymphocytes at late stages of differentiation. The occurrence of large-cell lymphoma against the background of B-CLL is called Richter syndrome. A new tumor may occur in lymph nodes, the spleen, the liver, and the gastrointestinal tract (GIT). GIT involvement in Richter syndrome is a very rare case; the authors found only six descriptions of such cases in available literature, and no such description in Russian literature. The authors adduce their own observation.