Triangular comparison of the agar diffusion method, the ABAC system and the Sensitre system for determination of bacterial sensitivity to aminoglycoside chemoantibiotics

Sala, A.; Raffaele, L.; Cappello, P.

Quaderni Sclavo di Diagnostica Clinica E di Laboratorio 17(1): 100-108

1981


ISSN/ISBN: 0033-4979
PMID: 7313065
Document Number: 5956
The in vitro activity of sisomicin, gentamicin, tobramycin and amikacin, four similar aminoglycosides, has been determined against 135 bacterial strains of Gram-negative bacilli representing 4 genera of common pathogens isolated from urinary tract infections. Comparison between three methods of antibiotic susceptibility tests: agar diffusion by Kirby-Bauer, semi-automatic technique using ABAC apparatus (Intertechnique, Sclavo) dilution method (MIC), has shown a considerable percentage of agreement, in almost all cases. The highest percentages of agreement have been shown for sisomicin and tobramycin. The authors analyze the role of the new techniques representing an advance in routine work.

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Triangular comparison of the agar diffusion method, the ABAC system and the Sensitre system for determination of bacterial sensitivity to aminoglycoside chemoantibiotics