Preparation of a dry red blood cell Trichinella antigenic diagnosticum for indirect hemagglutination test and evaluation of its efficiency
Tverdokhlebova, T.I.; Vaserin, I.I.
Meditsinskaia Parazitologiia i Parazitarnye Bolezni 2: 29-32
2005
ISSN/ISBN: 0025-8326 PMID: 15984615 Document Number: 585110
The present paper presents the stages of a process for manufacturing a dry red blood cell Trichinella antigenic diagnosticum for indirect hemagglutination test (IHAT) and the evaluation of its diagnostic efficiency. The diagnosticum is shown to be a 3% suspension lyophilized from formalinized and tanned sheep red blood cells on which an excretory-secretory antigen of invasion Trichinella larvae was absorbed in a dose of 100 mg/ml. The rather high sensitivity (98.7%) and specificity (97.3%) of IHAT using the Trichinella diagnosticum based on the excretory-secretory antigen allow it to be considered an effective method for diagnosis of human trichinosis.