Spontaneous heritable hydronephrosis in inbred mice. 1. Description, incidence, and distribution of lesions
Collins, G.R.; Goodheart, C.R.; Henson, D.
Laboratory Animal Science 22(3): 333-338
1972
ISSN/ISBN: 0023-6764 PMID: 4338696 Document Number: 56374
Hydronephrosis, unassociated with the 4 mutant genes known to produce hydronephrosis pleiotropically, and not fitting the description of other reported cases, was discovered in 4 inbred strains of mice. The afflicted mice were remarkably asymptomatic. Males (32%) showed a higher incidence than females (24.1%). Right kidneys were affected more frequently than left kidneys, in both sexes. Age did not appear to influence the incidence or expressivity. Histological studies suggested congenital ureteropelvic dyskinesia as the descriptive diagnosis.