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The influence of the dietary polyunsaturated fatty acids on the phagocyte's functional activity in rats

Trushina, E.N.; Mustafina, O.K.; Kulakova, S.N.

Voprosy Pitaniia 62(4): 9-11

2003

ISSN/ISBN: 0042-8833
PMID: 12968296
Document Number: 556541
The effects of dietary polyenoic fatty acids on superoxide anion production by peritoneal macrophages and on the phagocytosis by neutrophils were investigated in male Wistar rats after 3 months of feeding. Rats were fed isocaloric purified diet containing 24% fat (lard, sunflower oil and fish oil at a ratio of 49.0:6.1:1.1). Superoxide production and phagocytosis were increased after 3 months of feeding. The increased activity of mononuclear phagocytic system was confirmed by morphological investigation of peripheral lymphoid organs.

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