Top Abstract Purchase Related
Home
>
Node
>
Subnode

New substituted 4-thioxothiazolidin-2-one derivatives: synthesis and structural study

Chantegrel, J.; Albuquerque, J.C.; Guarda, V.L.; Perrissin, M.; Lima, M.C.A.; Galdino, S.L.; Brandão, S.S.; Thomasson, F.; Pitta, I.R.; Luu-Duc, C.

Annales Pharmaceutiques Francaises 60(6): 403-409

2002

ISSN/ISBN: 0003-4509
PMID: 12514507
Document Number: 543375
Synthesis and physico-chemical properties of some 3-benzyl- and 3-phenacyl-4-thioxo-5-benzylidenethiazolidin-2-one derivatives are described. Fifteen new compounds were synthesized from thiazolidin-2-one by thionation of the 4-carbonyle, alkylation of the 3-N and aldolisation-crotonisation of 5-CH(2) with aromatic aldehydes. Soon, these new compounds will be tested for their bacteriostatic activity.

Document emailed within 1 workday
Secure & encrypted payments

Brandão, S.S.; Guarda, V.L.; Pitta, I.R.; Chantegrel, J.; Perrissin, M.; Souza, V.M.; Galdino, S.L.; Thomasson, F.; Lima, M.C.; Leite, L.F.; Luu-Duc, C. 2000: Synthesis and structural study of substituted arylideneimidazolidines and arylidenebenzothiazines Bollettino Chimico Farmaceutico 139(2): 54-58
Albuquerque, J.F.; Galdino, S.L.; Chantegrel, J.; Thomasson, F.; Pitta, I.R.; Luu-Duc, C. 1997: Substituted thio-arylidene thiazolidinones: synthesis and structural study Annales Pharmaceutiques Francaises 55(5): 201-205
Ersan, S.; Nacak, S.; Acar, N.; Noyanalpan, N. 1997: Synthesis and antimicrobial activity of 1-dialkylaminomethyl- 2-(p-substituted phenyl)-5-substituted benzimidazole derivatives Arzneimittel-Forschung 47(4): 410-412
Wagner, G.; Voigt, B. 1978: Synthesis of 4-substituted 1-amidino- and 6-substituted 2-amidinonaphthyl derivatives with ketone and alcohol structure Die Pharmazie 33(9): 568-572
Bahekar, S.S.; Shinde, D.B. 2003: Synthesis and anti-inflammatory activity of some [2-amino-6-(4-substituted aryl)-4-(4-substituted phenyl)-1,6-dihydropyrimidine-5-yl]-acetic acid derivatives Acta Pharmaceutica 53(3): 223-229
Albuquerque, J.F.; Azevedo, L.C.; Galdino, S.L.; Chantegrel, J.; Pitta, I.R.; Luu-Duc, C. 1995: Synthesis and structural study of 5-arylidene thiazolidine-2,4-diones and 3-substituted-4-thio-imidazolidine-2-ones Annales Pharmaceutiques Francaises 53(5): 209-214
Maczyński, M.; Jezierska, A.; Zimecki, M.ł; Ryng, S.ła. 2003: Synthesis, immunological activity and theoretical study of new 5-substituted 3-methylisoxazole[5,4-d] 1,2,3-triazin-4-one derivatives Acta Poloniae Pharmaceutica 60(2): 147-150
Balbi, A.; Roma, G.; Mazzei, M.; Sottofattori, E.; Cadel, S.; Schiantarelli, P. 1989: Chemistry and pharmacology of pyrane derivatives. XVII. Synthesis of substituted 2-(dialkylamino)-3-formylchromones and their tricyclic derivatives Farmaco 44(6): 565-577
Milczarska, B.; Foks, H.; Sokołowska, J.; Janowiec, M.; Zwolska, Z.; Andrzejczyk, Z. 1999: Studies on pyrazine derivatives. XXXIII. Synthesis and tuberculostatic activity of 1-[1-(2-pyrazinyl)-ethyl]-4-N-substituted thiosemicarbazide derivatives Acta Poloniae Pharmaceutica 56(2): 121-126
Thunus, L. 1975: Synthesis of some 3-substituted 4-piperazinylpyridine derivatives Annales Pharmaceutiques Francaises 33(10): 487-494
Thunus, L. 1974: Synthesis of several 5-substituted 2-piperazinylpyridine derivatives Annales Pharmaceutiques Francaises 32(7-8): 443-446
Russo, F.; Santagati, M.; Santagati, A. 1978: Synthesis of 2-substituted derivatives of 5H-1,2,4-thiadiazolo[3,2-a] [1,3,5]triazin-5-one Il Farmaco; Edizione Scientifica 33(1): 26-39
Turkevich, M.M.; Grom, O.L. 1976: Synthesis and transformation of N4-substituted derivatives of thiazolidindion-2,4-thiosemicarbazone-4 Farmatsevtychnyi Zhurnal 31(3): 77-78
Fadl, T.A.; Hasegawa, T.; Youssef, A.F.; Farag, H.H.; Omar, F.A.; Kawaguchi, T. 1995: Synthesis and investigation of N4-substituted cytarabine derivatives as prodrugs Die Pharmazie 50(6): 382-387
el-Shaaer, H.M.; Abdel-Aziz, S.A.; Allimony, H.A.; Ali, U.F.; Abdel-Rahman, R.M. 1997: Synthesis and antimicrobial activities of some new 2-substituted benzoxazole/benzothiazole derivatives Die Pharmazie 52(8): 585-589
Grover, A.; Dwivedy, I.; Singh, A.K.; Ray, S.; Singh, M.M.; Kamboj, V.P. 1991: Synthesis and pregnancy-inhibiting activity of 7-substituted androst-5-ene derivatives Steroids 56(9): 477-480
Brancaccio, G.; Lettieri, G.; Monforte, P.; Larizza, A. 1982: Synthesis and pharmacological properties of some 2-substituted dibenz[2,3:6,7]-3a,12b-dihydrooxepin[4,5-d]1,3-dioxolane derivatives Il Farmaco; Edizione Scientifica 37(11): 711-718
El-Naggar, A.M.; Ahmed, F.S.; El-Salam, A.M.; El-Gazzar, M.A. 1982: Synthesis and biological activity of some new substituted aminoacyl-carbazole derivatives. Part Ii Il Farmaco; Edizione Scientifica 37(7): 494-500
Zuo, Z.-z.; Zhong, H.; Cai, T.; Bao, Y.; Liu, Z.-q.; Liu, D.; Zhao, L.-x. 2015: Design, synthesis and antiproliferative activities of artemisinin derivatives substituted by N-heterocycles Yao Xue Xue Bao 50(7): 868-874
Fayed, A.A.; Amr, A.E.-G.E.; Al-Omar, M.A.; Mostafa, E.E. 2014: Synthesis and antimicrobial activity of some new substituted pyrido[3',2':4,5]thieno[3,2-d]-pyrimidinone derivatives Bioorganicheskaia Khimiia 40(3): 335-340