Hybrid recombinant proteins: structure, properties and use

Urakov, N.N.; Veriasova, G.V.; Sokov, B.N.; Kavyzina, L.I.; Sergeeva, N.L.

Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 4: 46-51

1994


ISSN/ISBN: 0869-6047
PMID: 7516767
Document Number: 5393
The paper deals with the problem pertaining to immunotoxins which consist of two components, namely: catalytic (effector) and receptor-binding (ligand) ones. The immunotoxins are promising pharmaceutical drugs of a new generation, which are successfully used in clinical practice to treat tumor diseases, allergy, AIDS, and to transplant organs and tissues. Immunotoxins for the therapy of diabetes, autoimmune diseases, and bacterial, viral, and parasitic infections are being developed.

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Hybrid recombinant proteins: structure, properties and use