Study on the biocompatibility and toxicology of biomaterials--poly (epsilon-caprolactone)
Chen, J.; Huang, C.; Chen, Z.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 17(4): 380-382
2000
ISSN/ISBN: 1001-5515 PMID: 11211818 Document Number: 520344
Four observation indexes were selected to evaluate the biocompatibility and toxicology of biodegradable materials poly(epsilon-caprolactone)(PCL), which is synthesized in our laboratory using Ti(OBu)4 as an initiator. The results showed that PCL films had a mild inflammatory reaction in the early days of planting and after 3 months the inflammation basically disappeared. We conclude that PCL material possesses good biocompatibility and has a good developmental prospect.