A case of biloma caused by early complications of hepatic artery infusion chemotherapy
Miyazaki, O.; Hayakawa, M.; Nosaka, S.; Baba, K.; Iida, S.; Imanishi, Y.; Enomoto, T.; Ihara, A.; Tanaka, I.; Hagiwara, M.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 27(5): 749-752
2000
ISSN/ISBN: 0385-0684 PMID: 10832446 Document Number: 519671
We report a 70-year-old male who had biloma as an early complication of hepatic artery infusion chemotherapy. The patient had a history of subtotal gastrectomy for a advanced gastric cancer. Two years after the primary operation on the stomach, a solitary metastatic liver tumor was indicated by follow-up abdominal CT, and a segmental hepatectomy was performed. Soon after the hepatectomy, intraarterial catheter placement was performed via the left subclavian artery for preventive chemotherapy. Infusion chemotherapy of 10.5 g 5-FU and 75 mg CDDP was administered for a month, during which time the patient had liver dysfunction, fever, tenderness, and abdominal fullness. Abdominal CT revealed a large low density mass at a lateral segment of the liver which could not be seen on the previous CT image. Also, extravasation of contrast media was identified by angiography via the reservoir catheter. Using an interventional technique, percutaneous transhepatic drainage for biloma and extubation of the reservoir catheter were performed. The present case is thought to be of an early and rare complication of hepatic artery infusion chemotherapy. The etiology is discussed herein.