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Sclerosing cholangitis-induced biliary cyst formation: complication of hepatic artery infusion chemotherapy

Miyamoto, S.; Umekita, N.; Maeshiro, T.; Awane, Y.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 22(11): 1684-1686

1995

ISSN/ISBN: 0385-0684
PMID: 7574792
Document Number: 448500
A 60-year-old man underwent resection of a sigmoid colon adenocarcinoma, left hepatic lobe, part of segment 6 and 8, due to its metastasis. He received hepatic artery infusions of 5-FU total amount, 15.5 g. There was no recurrence in the liver, but he developed sclerosing cholangitis, and a large biliary cyst formed in segment 8. After drainage of the cyst by percutaneous-trans-hepatic approach, bile leakage persisted, and liver dysfunction was progressive. Sclerosing cholangitis-induced biliary cyst formation is rare. Occlusion, or necrosis of the peripheral bile duct may be the cause.

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