Extra- and intra-hepatic metastasis successfully treated with alternative chemotherapy with hepatic arterial infusion and systemic intravenous infusion after responding to hepatic metastasis from colon cancer by hepatic arterial infusion--a case report
Fujimoto, T.; Yoshimatsu, K.; Yokomizo, H.; Umehara, A.; Watanabe, K.; Otani, T.; Matsumoto, A.; Osawa, G.; Itagaki, H.; Ogawa, K.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 34(12): 1976-1978
2007
ISSN/ISBN: 0385-0684 PMID: 18219870 Document Number: 612615
A 72-year-old woman, who had the carcinoma of cecum with unresectable multiple liver metastases, underwent ileocecal resection and insertion of hepatic arterial infusion catheter. Hepatic arterial infusion (HAI) chemotherapy using Leucovorin. 5-FU caused to decrease liver metastases after an initiation of HAI. However, the metastatic nodule at the right lobe of lung was found. Then systemic chemotherapy with CPT-11 CDDP was performed alternately with HAI chemotherapy. After the initiation of revised regimen, all metastatic lesions were shrunk. We here in present the case of extra- and intra-hepatic metastasis successfully treated with alternative chemotherapy with hepatic arterial infusion and systemic intravenous infusion after responding to hepatic metastasis from colon cancer by hepatic arterial infusion.