Myelin basic protein. Structure, properties, function and role in diagnosing demyelinating diseases
Chekhonin, V.P.; Gurina, O.I.; Dmitrieva, T.B.; Semenova, A.V.; Savchenko, E.A.; Grigor'ev, M.E.
Voprosy Meditsinskoi Khimii 46(6): 549-563
2000
ISSN/ISBN: 0042-8809 PMID: 11234279 Document Number: 513601
Physico-chemical properties and biological role of myelin basic protein (MBP)--one of the main myelin membrane proteins are reviewed. The data on MBP phosphorylation, methylation, fatty acid acylation and on interaction with lipid molecules in the human and animals bodies are presented. Much attention has been paid to the discussion of the diagnostic and clinical significance of the MBP, as the marker of demyelinating process in the central and peripheral nervous system.