Myelin basic protein (MBP) in human gliomas: a study of twenty-five cases
Figols, J.; Iglesias-Rozas, J.R.; Kazner, E.
Clinical Neuropathology 4(3): 116-120
1985
ISSN/ISBN: 0722-5091 PMID: 2410174 Document Number: 246106
Twenty five gliomas (5 oligodendrogliomas, 8 oligoastrocytomas, 5 astrocytomas grades I-II, and 7 malignant astrocytomas-glioblastomas) were studied with the immunohistochemical technique avidin-biotin complex (ABC) for myelin basic protein (MBP). We found four patterns of positivity with variable degrees and frequencies in the different types of tumors. We believe this method can help in the diagnosis of non-characteristic gliomas, particularly oligoastrocytomas.