A case of carcinoma of lower lip showing excellent response to chemotherapy with UFT
Kasai, N.; Mutoh, Y.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 26(3): 373-376
1999
ISSN/ISBN: 0385-0684 PMID: 10065104 Document Number: 511597
We report a case of squamous cell carcinoma of the lower lip showing an excellent response to chemotherapy with UFT. A 68-year-old woman with a painless swelling of her lower lip was refereed to our service. This tumor was 19 x 18 mm with cauliflower surface, and induration was noted around the mass. The pathological diagnosis was squamous cell carcinoma of well-differentiated type. After chemotherapy with UFT (400 mg/day), the tumor became flat. It was then removed with a 7 mm-safety margin and the lower lip was reconstructed with an Abbe-Estlandar flap from the upper lip. Post-operative histological findings indicated a complete response. Wound healing was uneventful, and there has been no evidence of recurrence for these 6 months after the operation. This case is still under observation.