A case of refractory testicular cancer showing complete response to high-dose chemotherapy with autologous bone marrow transplantation
Ishii, H.; Osa, Y.; Okano, T.; Isaka, S.; Yasuda, K.; Shimazaki, J.; Komori, I.; Kodo, H.; Asano, S.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 16(10): 3483-3486
1989
ISSN/ISBN: 0385-0684 PMID: 2478078 Document Number: 330152
A patient with stage III testicular cancer was treated by 3 courses of BEP therapy and a partial response was obtained. Afterwards he underwent resection of pulmonary residual tumors and was treated by 2 courses of PE therapy immediately after operation. However, a new pulmonary tumor appeared after the first course of PE therapy was completed. He was treated by high-dose chemotherapy (etoposide 1200 mg/m2, cyclophosphamide 120 mg/kg, CDDP 60 mg/m2) with autologous bone marrow transplantation. Three weeks after high-dose chemotherapy his metastatic pulmonary tumor showed cavity formation which disappeared after 3 months. Fifteen months after the high-dose chemotherapy, no evidence of disease has been seen even without maintenance therapy.