Mycelial waste of tetracycline production as a component of the nutrient medium
Ponomareva, L.V.; Iakovlev, V.I.; Tsvetkova, N.P.; Krunchak, V.G.
Antibiotiki i Khimioterapiia 44(1): 11-13
1999
ISSN/ISBN: 0235-2990 PMID: 10095918 Document Number: 505065
A new composition of the nutrient medium for cultivation of the tetracycline-producing organism was developed with the fermentative hydrolysate of the tetracycline production mycelial waste as a source of nitrogen: 0.02 to 0.04 g/l by amino nitrogen. The use of the medium made it possible to increase the tetracycline yield by 5 to 25 per cent, to exclude cornsteep liquor from the medium composition, to provide a more efficient recovery of the waste and to significantly decrease the environment pollution.