Common properties of pharmacological agonists and antagonists of surface membrane receptors

Luĭk, A.I.; Prokopenko, V.V.; Tanchuk, V.I.; Kholodovich, V.V.; Semeniuta, I.V.

Voprosy Meditsinskoi Khimii 45(6): 514-524

1999


ISSN/ISBN: 0042-8809
PMID: 10761218
Document Number: 504019
Using experimental transcription model in vitro, and method of electron-topological calculations the elements of pharmacological and structural community have been found in the groups of physiologically active compounds (PAC), blocking and activating external cellular receptors. This finding confirms the necessity of subdivision special groups of bio-substrates blockators and activators for hierarchical classification, of PAC.

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