The anti-ulcer action of dibunol (Tonarol)
Zarudiĭ, R.F.; Myshkin, V.A.; Zarudiĭ, F.S.; Ismagilova, A.F.; Davydova, V.A.
Eksperimental'naia i Klinicheskaia Farmakologiia 61(5): 21-23
1998
ISSN/ISBN: 0869-2092 PMID: 9854627 Document Number: 496075
In experimental study of antiulcerative activity of dibunol on various models of gastric ulcers in rats the drug caused a marked antiulcerative effect in all of them, reduced the incidence of ulcer formation, and shortened the time of ulcer healing. In a model of "acetic" ulcer dibunol oil solution led to quick normalization of lipid peroxidation in the gastric mucosa, which was evidence of high antioxidant activity in cases of ulcer lesions.
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