Effect of L-lysine-a-oxidase on reproduction of herpes simplex type i virus in vitro
Smirnova, I.P.; Diorditsa, S.V.; Alekseev, S.B.; Zaĭtsev, I.Z.
Voprosy Meditsinskoi Khimii 44(4): 384-387
1998
ISSN/ISBN: 0042-8809 PMID: 9845927 Document Number: 494981
L-lysin-a-oxidase (LO), a fungal enzyme catalysing oxidative deamination of L-lysin, was used for the inhibition of the reproduction of herpes simplex virus type 1 (HSV-1). Antiviral activity of LO was tested in vitro. The expression of viral antigens and CPE of HSV-1 was inhibited by LO at a concentration 0.7 mg/ml.
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