Comparative analysis of tests on in vitro and in vivo quantitative assessment of the immunogenicity of tick-borne encephalitis vaccine
El'bert, L.B.; Vorovich, M.F.; Timofeev, A.V.
Voprosy Virusologii 43(5): 236-238
1998
ISSN/ISBN: 0507-4088 PMID: 9864830 Document Number: 491151
Many-year routine use of EIA as an in vitro test demonstrated it as a highly reproducible and technological test for assessing the efficacy of vaccine against tick-borne encephalitis and its semiproducts at the intermediate stages of vaccine production. The reproducibility of mouse protection test is notably inferior to that of EIA.
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