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Blast transformation reaction of the peripheral blood lymphocytes from persons inoculated with a tick-borne encephalitis vaccine

Shalamberidze, T.D.; Dzagurov, S.G.; Karpovich, L.G.; Vorob'eva, M.S.; Blokha, V.V.

Voprosy Virusologii 4: 431-434

1981

ISSN/ISBN: 0507-4088
PMID: 7303627
Document Number: 177063
The indices of blast transformation of lymphocytes to polyclonal mitogens of phytohemagglutinin (PHA) and Pokeweed mitogen (PWM) and to tick-borne encephalitis virus antigen (TBE) were studied in 80 individuals in the course of vaccination against tick-borne encephalitis. In the time course of vaccination reactions of blast transformation of lymphocytes was found to decrease to PHA and to increase to TBE and PWM antigens; spontaneous blast transformation also increased. Increased blast transformation reaction to TBE and PWM antigen correlated with the results of serological studies.

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