Efficiency of coadministration of immunomodulators and vaccine in an experiment on tick-borne encephalitis
Barinskiĭ, I.F.; Lazarenko, A.A.; Alimbarova, L.M.; Davydova, A.A.
Voprosy Virusologii 56(4): 45-47
2011
ISSN/ISBN: 0507-4088 PMID: 21899071 Document Number: 655462
Experiments on a tick-borne encephalitis (TBE) model in CBA and BALB/c mice demonstrated that immunomodulators (ridostin, polyribonate, and peptidoglycan-160) and a specific vaccine against TBE were significantly effective in increasing the level of a protective effect and life expectancy in the experimental group as compared to the control group. The findings allow one to recommend the immunomodulator ridostin in combination with the inactivated vaccine for the emergency prophylaxis of TBE in its virus-infected subjects in the foci of infection.