Changes in the state of monooxygenase system and lipid peroxidation under the effects of carcinogenic dust
Kuz'mina, L.P.; Bezrukavnikova, L.M.; Arkhipova, O.G.; Kasparov, A.A.
Meditsina Truda i Promyshlennaia Ekologiia 1997(4): 15-18
1997
ISSN/ISBN: 1026-9428 PMID: 9190266 Document Number: 476714
The work was aimed to study relationship of monooxygenase system and lipid peroxidation in experiments and in clinical group. The examinees were workers engaged into graphite ware production and exposed to low fibrogenic dust of coke and graphite with carcinogens (including 3,4-benzpyrene). The experimental data and examination materials prove the carcinogens to alter seriously those systems. Long stimulation of monooxygenase system and activation of lipid peroxidation could result in more intensive carcinogenic effects of polycyclic aromatic hydrocarbons being a component of coal pitch.