The endoscopic assessment of the effect of ranitidine and pirenzepine on the manifestations of the gastropathy induced by nonsteroidal anti-inflammatory preparations
Karateev, A.E.; Murav'ev, I.V.; Nasonova, V.A.
Terapevticheskii Arkhiv 69(5): 67-69
1997
ISSN/ISBN: 0040-3660 PMID: 9235663 Document Number: 475738
Two antiulcer drugs, ranitidine and pirenzepine belonging to blockers of H2-receptors and selective M-cholinoblockers, respectively, were compared by efficacy against erosive and ulcer lesions in the upper gastrointestinal mucosa. A total of 62 rheumatics were examined. In patients treated by nonsteroid antiinflammatory drugs irrespectively of the mode of their administration the highest response was shown by ranitidine while pirenzepine efficacy proved poor.