Uric acid metabolism abnormalities in IgA nephropathies
Konopielko, Z.; Zawadzki, J.; Wyszyńska, T.
Pediatria Polska 71(4): 327-330
1996
ISSN/ISBN: 0031-3939 PMID: 8975220 Document Number: 463963
The possibility of uric acid tract stones forming was analysed in 12 children with IgA nephropathy (group I) and 10 children with other hematuric glomerulopathies (group II). Elevated serum uric acid level and higher urinary excretion was found only in children with IgAN during exacerbation of the disease. Uric acid nephrolithiasis was found only in children with IgA nephropathy. The prophylactic treatment (proper diet, high fluid intake, adjusting urinary pH to 6.5-6.8) was effective in decreasing the number of exacerbations, urinary tract infections and formation of uric acid stones.