Simultaneous determination of plasma and urinary uric acid, xanthine, hypoxanthine, allopurinol, oxipurinol, orotic acid, orotidine and creatinine by high-performance liquid chromatography
Miyazaki, H.; Matsunaga, Y.; Yoshida, K.; Arakawa, S.; Hashimoto, M.
Journal of Chromatography 274: 75-85
1983
ISSN/ISBN: 0021-9673 PMID: 6874855 Document Number: 218160
A new high-performance liquid chromatographic procedure is described for the simultaneous determination of plasma and urinary uric acid, xanthine, hypoxanthine, allopurinol, oxipurinol, orotic acid and orotidine whose quantities are varied by allopurinol treatment in man. Creatinine was also measurable. The method was established by high-performance liquid chromatography and gas chromatography-mass spectrometry.