Development of technology for isolation and purification of gentamicin using sorption without filtration
Mikhaĭov, V.A.; Kharechko, A.T.; Sadovoĭ, N.V.; Petrov, P.P.; Demina, L.V.; Zhdanovich, I.V.; Bul'cheva, M.S.; Iakhontova, L.F.; Iarotskiĭ, S.V.
Antibiotiki i Khimioterapiia 41(10): 19-21
1996
ISSN/ISBN: 0235-2990 PMID: 9027287 Document Number: 462526
A technology for isolation and purification of gentamicin from nonfiltered fermentation broth with the use of sorption-pulsory columns was developed as a result of the research work. The practical application of the technology will increase the yield from 30 to 57 per cent and reduce the content of the minor admixtures in the final product up to 5 per cent in comparison to the currently used process.