The factors in local protection of the lungs and the status of cellular immunity in patients before and after thoracic operations
Vinnitskiĭ, L.I.; Timerbaev, V.K.; Vyzhigina, M.A.; Pletsityĭ, A.D.; Orlov, L.I.; Mustafin, A.K.
Anesteziologiia i Reanimatologiia 3: 18-21
1996
ISSN/ISBN: 0201-7563 PMID: 8967610 Document Number: 461486
Twenty-seven patients operated on the lungs and heart (aortocoronary bypass surgery) were examined. Cellular immunity parameters were studied in venous blood, and the function of immunocompetent cells, status of the surfactant system, and albumin level were assessed in the bronchoalveolar washings off. An impairment of the T-component of cellular immunity (T-suppressors), reduced level of alveolar macrophages and of their phagocytic activity, reduced activity of the surfactant system, and increased albumin content in the bronchoalveolar lavage fluid were revealed in patients with a complicated course of the postoperative period. In patients with a smooth course of the postoperative period these shifts were less expressed. The data indicate the necessity of antibacterial and immunomodulated therapy in such patients before and after surgery.