Urinary microflora and the status of local immunity in children with cystitis
Sentsova, T.B.; Bobkova, V.P.; Iatsyk, P.K.; Aiazbekov, E.A.; Ulisko, I.N.; Sarkisian, A.A.
Pediatriia 2: 19-23
1990
ISSN/ISBN: 0031-403X PMID: 2190167 Document Number: 356656
Study of the enzymatic and adhesive properties of E. coli isolated from the urine of children with cystitis has demonstrated that P-fimbriae, DNAase- and phosphatase-positive strains with pronounced hemolyzing and metabolic properties mostly occurred in children with associated cystitis and chronic obstructive pyelonephritis. In children suffering from cystitis, the changes on the part of local immunity manifested by the decrease of the content of SIgG in the urine and by the lack of SIgA1 and SIgA2. In children with a disease standing up to 3 years, the synthesis of IgA turned out dominant in the mucous membrane of the neck of the urinary bladder and in the trigone of the bladder, with IgG and IgM output being less intensive. The authors have proved the efficacy of the treatment with tomicide instilled into the urinary bladder of children suffering from cystitis.