Differential characteristics of the temperature-sensitive period of the lawcp1 mutation on the basis of macrochaetae overexpression in Drosophila
Simonova, O.B.; Petruk, S.F.; Korochkin, L.I.
Genetika 32(3): 445-447
1996
ISSN/ISBN: 0016-6758 PMID: 8723638 Document Number: 455951
Temperature-sensitive periods (TSPs) of lawc-p1 mutations were studied via the frequencies of arising of extras macrochaetae for each macrochaeta type separately. TSPs for the formation of extras macrochaetae of original classes were unevenly distributed within larval instars II and III. It was found that macrochaetae of different types differed from one another in their temperature sensitivity. The TSP of development of macrochaetae belonging to new ectopic classes was multiphase, with the first phase at larval instar II, and the second phase, at the prepupal to early pupal stage. It is assumed that in Drosophila, the products of the lawc gene participate, along with other genes, in the development of the nervous system through regulation of ac-sc expression, both in proneural clusters and outside them.